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. 2020 Mar 24;11:345. doi: 10.3389/fphar.2020.00345

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Copyright © 2020 Wu, Yang, Liu, Yin, Gong and Zhu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Results of puerarin and daidzein on RAW 264.7 cells. RAW264.7 cells were incubated with LPS (1 µg/mL) for 24 h and then treated with puerarin or daidzein (50, 75, or 100 µM) for 24 h. The effects of puerarin (A) or daidzein (B) on the viability of RAW264.7 cells using the CCK-8 assay. Production of IL-6 (C) and IL-4 (D) was determined by ELISAs. mRNA expression of NF-κBIA (E) and BCL2 (F) and PTGS2 (G) was determined by qRT-PCR. ##p < 0.01 versus blank control group. *p < 0.05 LPS-treated group. **p < 0.01 LPS-treated group.