Table 4.
Predicted amino acids of the HA1 gene of the isolated H5N8 isolates compared to other H5N8 viruses.
| RBS | HA amino acid substitutions | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Virus | Cleavage site | 222 | 224 | 72 | 104 | 150 | 162 | 180 | 191 | 293 | 285 | 358 |
| A/Bluebird/Aswan/MEVACF24/2017 | PLREKRRKRGLF | Q | G | S | D | A | N | Y | M | K | V | G |
| A/Quail/Sharkia/MEVACF25/2016 | PLREKRRKRGLF | Q | G | S | D | A | N | Y | M | K | M | G |
| A/chicken/Qalubia/MEVACF33/2017* | PLREKRRKRGLF | Q | G | I | G | P | K | Y | L | K | M | W |
| A/Greenfinch/Egypt/MEVAC F26/2016* | – | – | – | – | D | A | N | F | M | K | – | – |
| A/Chicken/Egypt/MEVAC F35.2/2017* | – | – | – | – | D | A | N | Y | M | K | – | – |
| A/green-winged teal/Egypt/877/2016 | PLREKRRKRGLF | Q | G | S | D | A | N | Y | M | K | V | G |
| A/Common-coot/Egypt/CA285/2016** | PLREKRRKRGLF | Q | G | S | D | A | N | Y | M | K | V | G |
| A/duck/DRC/17RS882-5/2017 | PLREKRRKRGLF | Q | G | S | D | A | N | Y | M | R | V | G |
| A/chicken/Israel/881/2016 | PLREKRRKRGLF | Q | G | S | D | A | N | Y | M | K | V | G |
*Partial sequence analysis of HA1 (aa 92 to 204 according to H5 numbering).
**First isolated H5N8 from wild birds in Egypt.