TABLE 11 .
Disposition of Mixture Components in Offspring Relative to TCDD
| Dose μg TEQ/kg | TCDF | PCDD | 1-PeCDF | 4-PeCDF | OCDF | PCB77 | PCB126 | PCB169 |
|---|---|---|---|---|---|---|---|---|
| Note. ND = compound not detected. Tissue disposition data presented in Chen et al., 2001. Values were calculated as follows: the percent dose of the congener/the percent dose of TCDD. Values are means ± SD (n = 4). | ||||||||
| GD 16 | ||||||||
| 0.05 | 0.08 ± 0.03 | 0.09 ± 0.01 | ND | 0.03 ± 0.01 | ND | 0.05 ± 0.05 | 0.72 ± 0.04 | 0.68 ± 0.03 |
| 0.2 | 0.08 ± 0.02 | 0.11 ± 0.02 | 0.02 ± 0.02 | 0.04 ± 0.01 | 0.01 ± 0.01 | 0.02 ± 0.01 | 0.49 ± 0.07 | 0.58 ± 0.08 |
| 0.8 | 0.11 ± 0.02 | 0.16 ± 0.05 | 0.02 ± 0.01 | 0.04 ± 0.02 | 0.003 ± 0.001 | 0.01 ± 0.003 | 0.37 ± 0.07 | 0.49 ± 0.11 |
| 1.0 | 0.15 ± 0.03 | 0.28 ± 0.06 | 0.11 ± 0.04 | 0.14 ± 0.03 | 0.01 ± 0.01 | 0.02 ± 0.01 | 0.29 ± 0.04 | 0.37 ± 0.05 |
| GD 21 | ||||||||
| 0.05 | ND | 0.36 ± 0.03 | ND | 0.12 ± 0.01 | ND | 0.01 ± 0.01 | 0.21 ± 0.04 | 0.18 ± 0.03 |
| 0.2 | 0.01 ± 0.02 | 0.47 ± 0.09 | ND | 0.13 ± 0.04 | 0.01 ± 0.002 | 0.003 ± 0.002 | 0.25 ± 0.07 | 0.21 ± 0.06 |
| 0.8 | ND | 0.36 ± 0.05 | 0.02 ± 0.003 | 0.09 ± 0.02 | 0.005 ± 0.002 | 0.003 ± 0.001 | 0.24 ± 0.02 | 0.24 ± 0.03 |
| 1.0 | ND | 0.39 ± 0.15 | ND | 0.11 ± 0.04 | 0.007 ± 0.002 | 0.003 ± 0.002 | 0.28 ± 0.09 | 0.27 ± 0.10 |
| PND 4 | ||||||||
| 0.05 | 0.17 ± 0.03 | 0.81 ± 0.20 | 0.18 ± 0.02 | 0.29 ± 0.05 | 0.01 ± 0.003 | 0.02 ± 0.01 | 0.88 ± 0.11 | 0.75 ± 0.16 |
| 0.2 | 0.02 ± 0.01 | 0.80 ± 0.08 | 0.04 ± 0.02 | 0.19 ± 0.02 | 0.01 ± 0.004 | 0.001 ± 0.001 | 0.93 ± 0.11 | 0.97 ± 0.15 |
| 0.8 | 0.004 ± 0.003 | 0.76 ± 0.12 | 0.03 ± 0.002 | 0.16 ± 0.03 | 0.02 ± 0.009 | 0.0006 ± 0.0008 | 0.82 ± 0.15 | 0.98 ± 0.16 |
| 1.0 | 0.004 ± 0.0008 | 0.67 ± 0.14 | 0.03 ± 0.008 | 0.14 ± 0.03 | 0.02 ± 0.006 | 0.0004 ± 0.0002 | 0.75 ± 0.15 | 0.88 ± 0.18 |