TABLE 3 .
EROD Activity in Maternal and Fetal Hepatic and Placental Microsomes at GD 21
| Maternal | Fetala | Placentaa | ||||
|---|---|---|---|---|---|---|
| Dose μg/kg | TCDD | TEQ mixture | TCDD | TEQ mixture | TCDD | TEQ mixture |
| Note. Units of activity are pmol/min/mg protein. | ||||||
| aValues are litter means with four fetuses or placentas per litter ± SE (n = 5). | ||||||
| *Significantly different from equivalent TCDD dose p < 0.05. | ||||||
| **Significantly different from equivalent TCDD dose p < 0.01. | ||||||
| Control | 30.5 ± 5.4 | 40.3 ± 4.0 | 0.6 ± 0.6 | 0.3 ± 0.2 | 0.23 ± 0.14 | 0.24 ± 0.11 |
| 0.05 | 69.19 ± 6.6 | 76.8 ± 6.3 | 0.9 ± 0.3 | 0.5 ± 0.2 | 0.56 ± 0.17 | 0.16 ± 0.03* |
| 0.2 | 390.8 ± 41.5 | 281.0 ± 22.8 | 1.9 ± 0.5 | 1.0 ± 0.5 | 0.68 ± 0.36 | 0.53 ± 0.31 |
| 0.8 | 794.7 ± 53.9 | 843.0 ± 8.4 | 67.3 ± 10.0 | 18.2 ± 1.2** | 2.74 ± 1.46 | 0.88 ± 0.31 |
| 1.0 | 1021.0 ± 109.4 | 1181.4 ± 108.0 | 97.9 ± 31.1 | 53.1 ± 14.1 | 1.74 ± 0.74 | 0.72 ± 0.09 |