TABLE 4 .
EROD Activity in Maternal and Pup Hepatic Microsomes at PND 4
Maternala | Pupb | |||
---|---|---|---|---|
Dose μg/kg | TCDD | Mixture | TCDD | Mixture |
Note. Units of activity are pmol/min/mg protein. | ||||
aValues are means (n = 5) ± SE. | ||||
bValues are litter means (n = 5) with four pups per litter ± SE. | ||||
*Significantly different from equivalent TCDD dose p < 0.05. | ||||
**Significantly different from equivalent TCDD dose p < 0.01. | ||||
***Significantly different from equivalent TCDD dose p < 0.001. | ||||
Control | 27.4 ± 5.0 | 44.6 ± 5.6* | 5.7 ± 0.9 | 5.0 ± 0.5 |
0.05 | 51.9 ± 4.2 | 48.3 ± 4.2 | 109.3 ± 23.1 | 83.2 ± 25.0 |
0.2 | 248.4 ± 19.1 | 121.2 ± 10.4** | 421.5 ± 41.6 | 284.3 ± 42.3 |
0.8 | 662.9 ± 25.6 | 354.9 ± 37.1*** | 786.3 ± 58.3 | 483.6 ± 77.4* |
1.0 | 718.2 ± 19.2 | 175.8 ± 17.5*** | 856.7 ± 47.2 | 611.0 ± 103.2* |