Table 2.
Distribution of MBL2 Haplotypes in Cases and Controls
| Haplotype | Haplotypes, No. (%), by Study Group(s) |
SEP vs SELN |
SEP vs (SELP + SELN) |
|||||
|---|---|---|---|---|---|---|---|---|
| SEP (n = 326) | SELP (n = 238) | SELN (n = 128) | SELP + SELN (n = 366) | OR (95% CI) | P a | OR (95% CI) | P a | |
| MBL2* LXPA | 41 (12.6) | 23 (9.7) | 21 (16.4) | 44 (12) | … | NS | … | NS |
| MBL2* LYQC | 93 (28.5) | 77 (32.3) | 31 (24.2) | 108 (29.5) | … | NS | … | NS |
| MBL2* LYQA | 93 (28.5) | 70 (29.4) | 37 (28.9) | 107 (29.3) | … | NS | … | NS |
| MBL2* HYPA | 15 (4.6) | 19 (8) | 13 (10.2) | 32 (8.7) | 0.4 (.18–1) | .048 | 0.5 (.25–.98) | .03 |
| MBL2* LYPA | 84 (25.8) | 49 (20.6) | 26 (20.3) | 75 (20.5) | … | NS | … | NS |
| Low expression of MBL2* | ||||||||
| LYQC + LXPA | 134 (41.1) | 100 (42) | 52 (40.6) | 152 (41.5) | … | NS | … | NS |
| High expression of MBL2* | ||||||||
| HYPA + LYQA + LYPA | 192 (58.9) | 138 (58) | 76 (59.4) | 214 (58.5) | … | NS | … | NS |
Percentages may not sum to 100%, because of rounding errors. Study groups were as follows: the SEP group (cases) was composed of individuals who tested positive for Schistosoma eggs, the SELP group (controls) was composed of individuals who tested positive for Schistosoma antigens by enzyme-linked immunosorbent assay (ELISA), and the SELN group (controls) was composed of individuals who tested negative for Schistosoma antigens by ELISA and negative for Schistosoma eggs.
Abbreviations: CI, confidence interval; NS, not significant; OR, odds ratio.
a Adjusted by the Benjamini-Hochberg procedure.