Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Jul 3;147(1):255–269. doi: 10.1093/toxsci/kfv127

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author 2015. Published by Oxford University Press on behalf of the Society of Toxicology. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com

This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.

PMC Copyright notice

FIG. 7. — Effects of polychlorinated biphenyl (PCB) 101, 153, and 180 alone (A and C) or in combination (B and D), on lipopolysaccharide (LPS)-induced TLR4 and CD14 mRNA expression. J774A.1 macrophages were exposed to PCBs at 300 nM, alone or mixed, in the presence of LPS (10 ng/ml) for 4 h. Therefore, cells were lysed to collect RNA, as described in Materials and Methods section. The mRNA expression levels were analyzed by real-time PCR. Data are means ± SEM of 3 independent experiments. As specified in the Materials and Methods section, when PCBs were used in combination, final concentration of pollutants was always 300 nM. **P < .01 and ***P < .001 versus untreated cells; ^#P < .05; ^##P < .01 and ^###P < .001 versus LPS-treated cells.