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. 2012 Jul 24;207(9):1433–1441. doi: 10.1093/infdis/jis476

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© The Author 2012. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

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Figure 1. — Evolutionary relationships among characterized and cohort human rhinovirus (HRV) sequences assigned to the genus Enterovirus. The evolutionary history was inferred using the neighbor-joining method in MEGA5 [37, 38]. The optimal tree is shown drawn to scale, with branch lengths in the same units as those of the evolutionary distances (base substitutions per site; maximum composite likelihood method [39]) The analysis involved 401 nucleotide sequences, including completely sequenced referenced types [40]. Sequences from this study (open diamonds) were included with previously characterized Human rhinovirus A (filled circles), Human rhinovirus B (filled triangles), Human rhinovirus C (filled diamonds), and enterovirus (open circles) types.