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. 2018 Jan 24;218(7):1037–1044. doi: 10.1093/infdis/jiy036

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© The Author(s) 2018. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

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Figure 2. — Pulmonary immunohistochemistry and histopathology of the patient with hPPMV-1/NL/579/2003 infection. A, Diffuse alveolar damage, characterized by thickening of alveolar septa, flooding of alveolar lumina, and presence of hyaline membranes (hematoxylin and eosin [H&E] staining; original magnification ×4.) B, Higher magnification of A, showing single pulmonary alveole, where epithelial lining is replaced by hyaline membranes (H&E; original magnification ×40.) C, Avian paramyxovirus type 1 antigen visible as granular staining in cytoplasm of degenerate cell, suggestive of alveolar epithelial cell (immunoperoxidase stain for pigeon paramyxovirus type 1 [PPMV-1]; original magnification ×100.).