Table 2.
Antibiotic Susceptibility to Penicillin and Cefotaxime by Study Time Period
| Penicillin | n | Susceptibility (%) | ||
|---|---|---|---|---|
| S | I | R | ||
| Pre-PCV Era | 143 | |||
| Isolate location breakpoint | 96.7 | 3.3 | 0 | |
| Meningitis breakpoint | 46.1 | 53.9 | ||
| PCV7 Era | 483 | |||
| Isolate location breakpoint | 90.8 | 8.6 | 0.6 | |
| Meningitis breakpoint | 51.1 | 48.9 | ||
| PCV13 Era | 116 | |||
| Isolate location breakpoint | 88.2 | 3.4 | 8.2 | |
| Meningitis breakpoint | 64.7 | 35.3 | ||
| Cefotaxime | ||||
| Pre-PCV Era | 140 | |||
| Isolate location breakpoint | 91.3 | 8 | 0.7 | |
| Meningitis breakpoint | 72.1 | 18.6 | 9.3 | |
| PCV7 Era | 479 | |||
| Isolate location breakpoint | 91 | 6.8 | 2 | |
| Meningitis breakpoint | 80.4 | 10.2 | 9.4 | |
| PCV13 Era | 116 | |||
| Isolate location breakpoint | 98.3 | 1.7 | 0 | |
| Meningitis breakpoint | 90.5 | 7.8 | 1.7 | |
Abbreviation: PCV, pneumococcal conjugate vaccine.