Skip to main content
. 2019 Jul 10;57(Suppl 3):S318–S327. doi: 10.1093/mmy/myy138

Table 1.

Acute and subacute non-infectious respiratory complications in the immunosuppressed patient.

Clinical problem Common radiological features
Acute presentation (hours to days)
Pulmonary edema Cardiomegaly, upper lobe diversion, interstitial oedema and pleural effusions
Acute respiratory distress syndrome (ARDS) Bilateral ground glass, dependent consolidation, traction bronchiectasis
Diffuse alveolar hemorrhage Rapidly progressive ground glass changes
Engraftment syndrome Interstitial oedema and pleural effusions
Thoracic air leak syndrome Pneumothorax, pneumomediastinum, subcutaneous emphysema
Leukostasis Interstitial infiltrates and/or alveolar opacification
Subacute presentation (days to weeks)
Idiopathic pneumonia syndrome Diffuse bilateral infiltrates
Organizing pneumonia Peribronchial and peripheral air space opacification
Radiation pneumonitis Ground glass and consolidation within the radiation field developing into pulmonary fibrosis
Drug toxicity Bilateral alveolitis (ground glass infiltrates), developing into pulmonary fibrosis
Chronic presentations (weeks to months)
Pulmonary veno-occlusive disease Enlarged pulmonary arteries, smooth interlobular septal thickening, ground glass opacities
Lung graft versus host disease (GvHD) Mosaickism, progressive airway dilatation
Post transplant lymphoproliferative disorder (PTLD) Pulmonary nodules and mediastinal lymphadenopathy
Pleuroparenchymal fibroelastosis Fibrotic thickening of pleura and subpleural parenchyma
Nonclassifiable interstitial pneumonia (pulmonary fibrosis) Ground glass, peribronchial crazy paving, reticulation and traction-bronchiectasis