Table 2.
Clinical and necropsy data from PCP PCR-positive cats presented for necropsy examination. DSH = domestic short-haired cat; M = male; F = female; MN = male neutered; FN = female neutered; Young animals (age ≤ 1year); Adult (age > 1 year); BCS – body condition score; n/a = not available; nd = not done. –ve = negative; +ve = positive.
| No. | Lifestyle | Origin (Province) | Breed | Age* | Sex | BCS | Lung - Macroscopic | Lung - Histology (H&E) | Corona-virus (qPCR) | FPV (IHM) | FeLV | FIV | Presumptive cause of death | Pneumocystis lineage |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Family | Padua | Maine Coon | Young | F | Good | Inflamed areas with pulmonary consolidation in both lungs. Fibrin exudation. Presence of foam and whitish material in bronchi. | Focal granulomatous pneumonia with fibrinous exudation, abundant bacterial and congestive pneumonia. Rare fibrin thrombus in blood vessels. | nd | +ve | nd | nd | Gastro-enteritis | Lineage 1 |
| 2 | Family | Padua | Scottish Fold | Young | M | Poor | Oedema and pulmonary congestion at apical lobes | Atelectasis. Emphysema and alveolar oedema. | +ve | -ve | nd | nd | Peritonitis | Lineage 1 |
| 3 | Street | Padua | Italian DLH | Young | F | Good | Congestion of parenchyma. | Congestion of parenchyma. Alveolar oedema foci. | -ve | -ve | nd | nd | Catarrhal enteritis | Lineage 1 |
| 4 | Street | Padua | Italian DSH | Young | M | Poor | Lung collapsed. Fibrino-purulent bronchopneumonia | Fibrino-purulent necrotic bacterial pneumonia | nd | +ve | nd | nd | Pneumonia | Lineage 1 |
| 5 | Street | Padua | Italian DSH | Young | M | Good | Pulmonary congestion | nd | nd | nd | nd | nd | Catarrhal enteritis | Lineage 1 |
| 6 | Street | Padua | Italian DSH | Young | M | Poor | Absence of lung alterations | nd | +ve | +ve | nd | nd | Catarrhal-haemorrhagic enteritis | Lineage 1 |
| 7 | Street | Padua | Italian DSH | Young | M | Poor | Not reported | Autolysis. Presence of numerous bacteria. | -ve | +ve | nd | nd | Catarrhal haemorrhagic gastritis and enteritis | Lineage 1 |
| 8 | Street | Padua | Italian DSH | Young | M | Poor | Congestion of parenchyma. Atelectasis apical lobe | Pyogranulomatous pneumonia. | nd | nd | nd | nd | Pneumonia | Lineage 1 |
| 9 | Family | Rovigo | Italian DSH | Young | M | Good | Pneumonia and emphysema | Lymphocytic Interstitial pneumonia and fibrinopurulent thrombo-embolic dissemination. | -ve | nd | nd | nd | Pneumonia | Lineage 1 |
| 10 | Street | Padua | Italian DSH | Young | F | Good | Abdominal haemorrhage and hemoperitoneum | nd | nd | nd | nd | nd | Vehicular trauma | Lineage 1 |
| 11 | Family | Palermo | Italian DSH | Young | F | Good | Bilateral pleural effusion | Alveolar atelectasis, presence of bacteria in the alveoli. | +ve | -ve | -ve | -ve | Necrotic enteritis | Lineage 1 |
| 12 | n/a | n/a | n/a | Young | F | Good | Presence of coagulated blood in trachea. Haemorrhagic areas. | nd | nd | nd | nd | nd | Vehicular trauma | Lineage 1 |
| 13 | Street | Padua | Italian DSH | Adult | MN | Good | Pulmonary congestion | nd | nd | nd | nd | nd | Hepatic adenocarcinoma | Lineage 1 |
| 14 | Family | Venice | Italian DSH | Adult | MN | Good | Not reported | Alveolar oedema. | nd | nd | -ve | -ve | Hepatitis and catarrhal haemorrhagic enteritis | Lineage 1 |
| 15 | Street | Rovigo | Italian DSH | Adult | F | Poor | Not reported | nd | nd | nd | nd | nd | Vehicular trauma | Lineage 1 |
| 16 | Street | Venice | Italian DSH | Adult | F | Good | Pulmonary congestion and oedema | Oedema and alveolar congestion. | -ve | -ve | nd | nd | Necrotic superficial enteritis. Nephritis. | Lineage 1 |
| 17 | Street | Venice | Italian DSH | Adult | F | Poor | Pulmonary congestion and oedema | nd | nd | +ve | nd | nd | Chronic nephritis | Lineage 1 |
| 18 | Street | Padua | Italian DLH | Adult | F | Good | Congestion of parenchyma. | Alveolar oedema. | nd | nd | nd | nd | Vehicular trauma | Lineage 1 |
| 19 | Family | Padua | Italian DSH | Adult | M | Good | Pulmonary congestion and haemorrhage at apical lobes | Diffuse haemorrhage. | nd | nd | nd | nd | Vehicular trauma | Lineage 1 |
| 20 | Street | Padua | Italian DSH | Young | F | Good | Pleural and pericardial serum-hematic effusion; pulmonary congestion. | nd | -ve | -ve | nd | nd | Enteritis | Lineage 2 |
| 21 | Street | Venice | Italian DSH | Young | M | n/a | Pulmonary congestion | Lymphocytic interstitial pneumonia. | +ve | -ve | nd | nd | Vehicular trauma | Lineage 2 |
| 22 | Street | Padua | Italian DSH | Adult | M | Poor | Pulmonary congestion | Partial destruction of the parenchyma consisting of interstitial infiltration of round cells of lymphoid origin. | -ve | nd | +ve | -ve | Lymphoma | Lineage 2 |
| 23 | Family | Rovigo | Italian DSH | Adult | MN | Good | Pulmonary consolidation | Low preservation of cells due to freezing storage. | nd | nd | nd | nd | Enteritis | Lineage 2 |
| 24 | Street | Venice | Italian DSH | Adult | FN | n/a | Absence of lung alterations | nd | -ve | +ve | -ve | -ve | Haemorrhagic gastritis and catarrhal enteritis | Lineage 2 |