Table I.
Demographic and clinicopathological information of the 58 BC patients.
| METTL14 expression | ||||
|---|---|---|---|---|
| Characteristics | No. of patients | Low n (%) | High n (%) | P-value |
| Age (years) | 0.5992 | |||
| <60 | 28 | 15 (53.5) | 13 (46.5) | |
| ≥60 | 30 | 14 (46.7) | 16 (53.3) | |
| Typing | 0.9389 | |||
| Luminal A | 4 | 2 (50) | 2 (50) | |
| Luminal B | 33 | 16 (39.4) | 17 (60.6) | |
| HER-2+ | 9 | 5 (55.6) | 4 (44.4) | |
| Basal-like | 12 | 5 (41.7) | 7 (58.3) | |
| Microvascular invasion | 0.4297 | |||
| Yes | 27 | 12 (44.4) | 15 (55.6) | |
| No | 31 | 17 (54.8) | 14 (45.2) | |
| Nerve invasion | 0.6489 | |||
| Yes | 15 | 7 (46.7) | 8 (53.3) | |
| No | 43 | 23 (53.5) | 20 (46.5) | |
| TNM | 0.0483a | |||
| T1+T2 | 54 | 30 (55.6) | 24 (44.4) | |
| T3 | 4 | 0 | 4 (100) | |
| Pathological stage | 0.0827 | |||
| I+II | 47 | 22 (46.8) | 25 (53.2) | |
| III | 11 | 2 (18.2) | 9 (81.8) | |
| WHO | 0.0768 | |||
| I+II | 27 | 12 (44.4) | 15 (55.6) | |
| III | 31 | 7 (22.6) | 24 (77.4) | |
| Metastasis | 0.2389 | |||
| pN0+pN1 | 47 | 22 (46.8) | 25 (53.2) | |
| pN2+pN3 | 11 | 3 (27.3) | 8 (72.7) | |
a
P<0.05, represents a significant difference. BC, breast cancer; METTL14, methyltransferase like 14.