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. 2020 Feb 26;43(5):1387–1396. doi: 10.3892/or.2020.7519

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Copyright: © Yan et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 8. — Effects of α-solanine on tumor growth. BALB/c nude mice were injected subcutaneously with RKO cells. When the tumors were palpable, the mice were randomized to receive treatment with α-solanine, or DMSO as a control. (A) Tumor volume. (B) Tumor weight. (C) Mouse body weight. (D) Ki-67 expression was detected by immunohistochemistry (upper panel), apoptosis was evaluated by the TUNEL assay (lower panel) and observed under a microscope (magnification, ×200). (E) Ki-67 expression was quantified by Image-Pro Plus 6.0 software and expressed as fold of control. (F) Apoptosis was quantified by Image-Pro Plus 6.0 software. *P<0.05, **P<0.01 vs. control group.