Table IV.

Clinicopathologic associations of TOP2A expression in lung adenocarcinoma (N=72).

		Relative TOP2A expression
Clinical parameters	No. of cases	Low	High	P-value
Age (years)				0.237
>60	39	22	17
≤60	33	14	19
Sex				0.099
Male	37	15	22
Female	35	21	14
Smoking				1
Smoker	42	21	21
Non-smoker	30	15	15
Maximum diameter (cm)				0.003
<3	26	19	7
≥3	46	17	29
Lymphatic metastasis				0.812
Positive	41	21	20
Negative	31	15	16
Metastasis				0.607
M0	68	33	35
M1	4	3	1

TOP2A, DNA topoisomerase II α.