Table 2.
Subgroup Analyses: Accuracy Estimates
| Pooled Sensitivity (95% CI) | Pooled Specificity (95% CI) | |
|---|---|---|
| Influenza | ||
| Virus type | ||
| Influenza A | 68.1 (58.9–76.0) | 99.2 (98.5–99.6) |
| H1N1 | 54.0 (47.6–60.3) | 99.1 (98.5–99.5) |
| Influenza B | 71.0 (56.8–82.1) | 99.6 (99.2–99.8) |
| Influenza A+B | 61.1 (53.3–68.3) | 98.9 (98.4–99.3) |
| Population | ||
| Children | 66.1 (52.9–79.3) | 98.3 (97.2–99.5) |
| Adults | 34.1 (14.0–54.1) | 99.2 (98.2–100.0) |
| Point-of-care testing | 62.1 (47.6–74.7) | 98.4 (96.7–99.2) |
| Rapid test | ||
| QuickVue Influenza A+B | 44.6 (29.1–60.0) | 99.3 (98.8–99.9) |
| Sofia Influenza A+B | 75.3 (59.2–91.5) | 95.3 (91.5–99.2) |
| BinaxNow Influenza A&B | 44.1 (23.3–64.9) | 99.4 (98.6–100.0) |
| Directigen Flu A+B | 35.8 (11.8–59.7) | 99.2 (98.0–99.4) |
| mariPOC | 76.1 (53.5–98.7) | 99.4 (98.3–100.0) |
| RSV | ||
| Population | ||
| Children | 75.9 (73.1–78.5) | 98.5 (968–99.4) |
| Mixed | 70.9 (63.0–77.8) | 99.1 (95.9–99.8) |
| Point-of-care testing | 76.0 (69.8–81.2) | 99.1 (95.5–99.8) |
| Rapid test | ||
| BD Veritor RSV | 76.9 (71.0–82.8) | 98.9 (97.1–100.0) |
| BinaxNOW RSV | 72.2 (65.2–79.1) | 98.6 (96.5–100.0) |
| Sofia RSV | 80.0 (73.0–86.9) | 97.8 (93.8–100.0) |
Abbreviations: CI, confidence interval; RSV, respiratory syncytial virus.