Table 3.
Anthropometric and laboratory parameters variations in patients treated with Aripiprazole.
| Parameter | Baseline | 6 months | 12 months | Over time variation | |||
|---|---|---|---|---|---|---|---|
| n | Mean ± SD | n | Mean ± SD | n | Mean ± SD | p | |
| BMI (kg/cm2) | 44 | 20.02 ± 3.71 | 44 | 21.05 ± 3.78 | 44 | 22.01 ± 3.55 | <0.001 |
| Fasting glucose (mg/dL) | 44 | 85.55 ± 8.13 | 41 | 87.94 ± 8.92 | 43 | 88.48 ± 9.85 | 0.402 |
| Total cholesterol (mg/dL) | 44 | 152.46 ± 20.47 | 41 | 155.87 ± 23.7 | 43 | 159.52 ± 24.72 | 0.125 |
| Triglycerides (mg/dL) | 44 | 76.69 ± 46.41 | 41 | 87.6 ± 66.42 | 43 | 72.52 ± 33.76 | 0.9 |
| Prolactin (ng/mL) | 44 | 9.57 ± 9.96 | 41 | 3.92 ± 4.66 | 39 | 2.63 ± 3.1 | 0.072 |
| Systolic pressure (mmHg) | 44 | 104.97 ± 11.23 | 42 | 104.75 ± 13.53 | 43 | 107.2 ± 13.72 | 0.107 |
| Diastolic pressure (mmHg) | 44 | 60.31 ± 7.55 | 42 | 63.15 ± 8.43 | 43 | 63.03 ± 8.54 | 0.704 |
| Heart rate (BPM) | 44 | 76.29 ± 13.76 | 42 | 82.11 ± 12.44 | 43 | 82.69 ± 12.97 | 0.026a |
| Qt interval corrected | 44 | 402.76 ± 29.65 | 40 | 392.87 ± 43.67 | 38 | 402.01 ± 20.72 | 0.687 |
| White blood cells (μL) | 44 | 6,625.6 ± 1,721.33 | 39 | 6,167.22 ± 2,446.49 | 41 | 7,182.76 ± 3,194.2 | 0.882 |
| Neutrophil count (%) | 44 | 49.84 ± 8.77 | 39 | 52.98 ± 13.29 | 41 | 56.5 ± 10.23 | 0.223 |
a
The difference was statistically significant for baseline vs. 6 months and baseline vs. 12 months but not for 6 vs. 12 months.