Table 2.
Effects of six medicinal herbal extracts on MHV-A59
| EC50a | CC50b | SIc | |
|---|---|---|---|
| Cimicifuga rhizoma | 19.4 ± 7.0 | 239.0 ± 44.4 | 12.3 |
| Meliae cortex | 13.0 ± 1.4 | 334.3 ± 7.0 | 25.6 |
| Coptidis rhizoma | 2.0 ± 0.5 | 71.3 ± 7.2 | 34.9 |
| Phellodendron cortex | 10.4 ± 2.2 | 139.5 ± 81.3 | 13.4 |
| Sophora subprostrata radix | 27.5 ± 1.1 | 307.3 ± 6.6 | 11.1 |
| Moutan cortex radicis | 61.9 ± 6.1 | 598.7 ± 12.5 | 9.7 |
a
Determined as the concentration of extracts needed to inhibit the virus titer by 50% of the control value (cells without addition of extracts). Each value represents the mean ± S.D. from three independent experiments. The unit for EC50 values shown in the table is μg/ml.
b
Determined as the concentration of extracts necessary to reduce the cell viability to 50% of the control (cells without addition of extracts). Each value represents mean ± S.D. from three independent experiments. The unit for CC50 values shown in the table is μg/ml.
c
Selectivity index (CC50/EC50).