Table 2.
Characteristics of 10 patients infected by hCoV HKU1 in the winter–spring season 2005–2006
| Parameter | Patient number |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | |
| Sex | M | F | M | M | M | M | M | F | F | M |
| Age (year) | 66 | 1 | 1 | 2 | 12 | 51 | 1 | 50 | 3 | 20 |
| Underlying/concomitant disease | Multiple myeloma | Gastroenteritis | No | No | SCID | LTR | Pericarditis | LTR | HSCT, ALL | HSCT, AML |
| URTI | + | + | + | + | − | − | + | + | + | + |
| LRTI | − | − | − | − | + | + | − | − | − | − |
| HKU1 subtype | A | B | A | A | B | A | B | B | B | B |
| Clinical symptoms | ||||||||||
| Fever | + | + | − | + | − | − | − | − | − | + |
| Otalgia | − | − | − | + | − | − | − | − | − | − |
| Cough | − | − | − | − | + | − | − | − | − | − |
| Rhinorrhea | + | + | + | + | + | − | + | + | + | + |
| Sore throat | + | + | − | + | − | − | − | − | − | − |
| Wheezing | − | − | − | − | + | − | − | − | − | − |
| Bronchiolitis | − | − | − | − | − | − | − | − | − | − |
| Pneumonia | − | − | − | − | − | − | − | − | − | − |
| Diarrhea | − | + | − | − | − | − | − | − | − | − |
| Coinfection | − | − | Rhino | − | − | HCMV | hMPV-B | − | hPIV-3 + Rhino | − |
M, male; F, female; SCID, severe combined immune deficiency; LTR, lung transplant recipient; HSCT, hematopoietic stem cell transplant; ALL, acute lymphocytic leukemia; AML, acute myelocytic leukemia; URTI, upper respiratory tract infection; LRTI, lower respiratory tract infection; HCMV, human cytomegalovirus; hMPV-B, human metapneumovirus B; hPIV-3, human parainfluenzavirus type 3; Rhino, rhinovirus.