Table 2.
Characteristics of viruses that commonly cause acute gastroenteritis in humans
| Virus (family) | Size and structure | Genome composition | Classification | Epidemiology |
|---|---|---|---|---|
| Rotaviruses (Reoviridae) | 75 nm, triple-layered, wheel-shaped | 11 segments of dsRNA totalling 18.5 kb | Groups A–H | Endemic in children worldwide, winter outbreaks in temperate climates, small epidemics in the elderly |
| Within group A subgroups, G and P types | ||||
| Genotypes of all segments | ||||
| Caliciviruses (Caliciviridae) | About 30 nm, surface cup-shaped | ssRNA, 7.7 kb | Two genera infecting humans: noroviruses, sapoviruses | Epidemics in humans of all age groups |
| Enteric adenoviruses (Adenoviridae) | About 70 nm, icosahedral | dsDNA, 36 kb | Group F serotypes 40, 41 | Endemic in children |
| Astroviruses (Astroviridae) | About 30 nm, star-like appearance | ssRNA, 6.8 kb | Two genogroups, 19 genotypes | Epidemics in children and adults |
ds, double-stranded; ss, single-stranded.