Table 2.
Characteristics of 318 respiratory tract infections.
| Characteristic | Single | Coinf | None | RhV | Adv | CoV | PIV | RSV | Flu A | HMPV |
|---|---|---|---|---|---|---|---|---|---|---|
| Total (%) RTIs | 126 (40) | 87 (27) | 105 (33) | 111 (35) | 69 (22) | 48 (15) | 37 (12) | 35 (11) | 7 (2) | 14 (4) |
| Mean age (months) | 13.2 | 11.5 | 12.3 | 12.4 | 10.4 | 11.8 | 13.1 | 12.4 | 17.9 | 12.0 |
| n (%) male | 65 (52) | 50 (57) | 56 (53) | 69 (62) | 40 (58) | 29 (60) | 14 (38) | 17 (49) | 2 (29) | 8 (57) |
| Single infections only | ||||||||||
| Number (%) RTIs as single virus identified | 126 (100) | N/A | N/A | 50 (16) | 17 (5) | 14 (4) | 14 (4) | 20 (6) | 5 (2) | 5 (2) |
| Mean (range) of peak viral load (log copies/mL) | N/A | 5.0 (2.9, 7.9) | 6.5 (4.5, 9.2) | 6.2 (3.5, 8.5) | 7.9 (5.4, 9.4) | 7.1 (6.1, 8.1) | 6.9 (5.5, 9.4) | |||
| Mean duration (days) | 8.2 | 8.7 | 7.4a | 8.2 | 9.1 | 7.9 | 8.4 | 8.6 | 7.8 | 6.2 |
| n (%) fever | 67 (53) | 39 (46) | 44 (42) | 25 (50) | 8 (47) | 4 (29) | 6 (43) | 16 (80)b | 5 (100)c | 3 (60) |
| n (%) wheezing | 43 (34) | 34 (39) | 34 (32) | 17 (34) | 6 (35) | 3 (21) | 4 (29) | 10 (50)d | 0 (0) | 3 (60) |
| Mean days DC missed | 1.1 | 1.2 | 1.1 | 0.7b | 1.1 | 1.7 | 0.9 | 1.4 | 3 | 1 |
| Mean days work missed | 0.9 | 1.2 | 1.1 | 0.7d | 0.7 | 0.9 | 0.9 | 1.4 | 2.8 | 1 |
| n (%) HCP visits | 62 (49) | 44 (51) | 41 (39) | 18 (36) | 8 (47) | 5 (36) | 9 (64) | 16 (80)a | 2 (40) | 3 (60) |
| Co-infections only | ||||||||||
| Number (%) of RTIs with virus as co-infection | 61 (19) | 52 (16) | 34 (11) | 23 (7) | 15 (5) | 2 (0.6) | 9 (0.3) | |||
| Mean (range) of peak viral load, log copies/mL | N/A | 4.6 (2.5, 7.6) | 6.7 (2.8, 10.1) | 6.2 (2.5, 9.8) | 7.3 (3.7, 9.0) | 6.1 (3.6, 8.6) | 6.3 (4.0, 8.4) | |||
| Mean duration (days) | 8.6c | 8.6 | 8.8c | 8.3 | 9.1c | 9 | 9.3e | |||
| n (%) fever | 29 (48) | 22 (44) | 14 (41) | 10 (43) | 8 (53) | 1 (50) | 4 (44) | |||
| n (%) wheezing | 22 (36) | 19 (37) | 14 (41) | 8 (35) | 10 (67)f | 1 (50) | 4 (44) | |||
| Mean days DC missed | 1.2 | 1.2 | 1.2 | 1.3 | 1.8 | 0.5 | 1.8 | |||
| Mean days work missed | 1.2 | 1.1 | 1.1 | 1.3 | 1.9 | 0.5 | 1.1 | |||
| n (%) HCP visits | 30 (49) | 23 (44) | 16 (47) | 16 (70)b | 10 (67)d | 0 (0) | 5 (56) | |||
RhV, rhinovirus; AdV, adenovirus; CoV, human coronavirus; PIV, parainfluenza viruses; RSV, respiratory syncytial virus; flu A, influenza virus A; MPV, human metapneumovirus; RTIs, respiratory tract infections.
a
p = 0.001.
b
p = 0.002.
c
p = 0.02.
d
p = 0.01.
e
p = 0.007.
f
p = 0.009.