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Structures of acylguanidines inhibiting viral proteins. HMA inhibits Vpu of human immunodeficiency virus type 1, p7 of hepatitis C virus, M protein of dengue virus, E protein of severe acute respiratory syndrome coronavirus and 3Dpol of coxsackievirus B3. DMA inhibits Vpu. BIT225 inhibits Vpu and p7. Amiloride, EIPA and benzamil inhibit 3Dpol.
