Table 2.
Baseline characteristics by pathogenic group in the prospective Cough Complication Cohort (3C) Plus study 2013
| Baseline characteristic | Organism group | P-value | |||||||
|---|---|---|---|---|---|---|---|---|---|
| None (n = 299) | Viral (n = 151) | Bacterial (n = 120) | Both (n = 75) | ||||||
| Age (years), Mean (SD) | 51.4 | (17.8) | 50.4 | (17.8) | 49.5 | (18.5) | 45.0 | (19.2) | 0.049 |
| Sex, N (%) | 0.151 | ||||||||
| Male | 94 | (31.4) | 55 | (36.4) | 50 | (41.7) | 31 | (41.3) | |
| Female | 205 | (68.6) | 96 | (63.6) | 70 | (58.3) | 44 | (58.7) | |
| Duration of illness (days), Mean (SD) | 9.9 | (6.51) | 8.1 | (5.53) | 11.5 | (7.12) | 8.9 | (5.79) | <0.001 |
| Illness worsening, N (%) | 215 | (71.9) | 118 | (78.1) | 90 | (75.0) | 64 | (85.3) | 0.086 |
| Antibiotics prescribed, N (%) | 0.009 | ||||||||
| No | 67 | (22.4) | 34 | (22.5) | 37 | (30.8) | 10 | (13.3) | |
| Delayed | 29 | (9.70) | 15 | (9.93) | 12 | (10.0) | 17 | (22.7) | |
| Immediate | 203 | (67.5) | 102 | (67.5) | 71 | (59.2) | 48 | (64.0) | |
| Smoking status, N (%) | 0.211 | ||||||||
| Never | 124 | (41.5) | 55 | (36.4) | 46 | (38.3) | 30 | (40.0) | |
| Past | 90 | (30.1) | 40 | (26.5) | 37 | (30.8) | 14 | (18.7) | |
| Years since cessation, Mean (SD) | 15.6 | (14.3) | 24.8 | (17.6) | 13.2 | (12.9) | 16.8 | (15.6) | 0.003 |
| Current | 85 | (28.4) | 56 | (37.1) | 37 | (30.8) | 31 | (41.3) | |
| Pack-years, Mean (SD) | 19.8 | (17.1) | 17.4 | (15.6) | 20.9 | (28.7) | 18.3 | (19.0) | 0.824 |
| Symptoms, N (%) | |||||||||
| Blocked or runny nose | 202 | (67.6) | 123 | (81.5) | 79 | (65.8) | 63 | (84.0) | <0.001 |
| Fever | 129 | (43.1) | 86 | (57.0) | 67 | (55.8) | 50 | (66.7) | <0.001 |
| Muscle aches all over | 168 | (56.2) | 102 | (67.5) | 47 | (39.2) | 39 | (52.0) | <0.001 |
| Sputum | 203 | (67.9) | 117 | (77.5) | 86 | (71.7) | 67 | (89.3) | 0.001 |
| Crackles | 169 | (56.5) | 93 | (61.3) | 55 | (45.8) | 53 | (70.7) | 0.004 |
| Wheeze | 71 | (23.7) | 45 | (29.8) | 24 | (20.0) | 29 | (38.7) | 0.016 |
| Chills/shivering | 122 | (40.8) | 68 | (45.0) | 51 | (42.5) | 44 | (58.7) | 0.047 |
| Disturbed sleep | 244 | (81.6) | 134 | (88.7) | 108 | (90.0) | 67 | (89.3) | 0.049 |
| Wet or productive cough | 229 | (76.6) | 115 | (76.2) | 99 | (82.5) | 67 | (89.3) | 0.057 |
| Chest pain | 112 | (37.5) | 62 | (41.1) | 53 | (44.2) | 38 | (50.7) | 0.176 |
| Bronchial breathing | 13 | (4.3) | 10 | (6.6) | 7 | (5.8) | 8 | (10.7) | 0.211 |
| Shortness of breath | 238 | (79.6) | 118 | (78.1) | 85 | (70.8) | 61 | (81.3) | 0.213 |
| Diarrhoea | 33 | (11.0) | 19 | (12.6) | 20 | (16.7) | 7 | (9.33) | 0.362 |
| Confusion/disorientation | 19 | (6.35) | 12 | (7.95) | 8 | (6.67) | 9 | (12.0) | 0.401 |
| Dry cough | 188 | (62.9) | 96 | (63.6) | 85 | (70.8) | 51 | (68.0) | 0.420 |
| Headache | 165 | (55.2) | 88 | (58.3) | 71 | (59.2) | 46 | (61.3) | 0.735 |
| Vital Signs, Mean (SD) | |||||||||
| Respiratory rate (breaths/min) | 17.1 | (3.96) | 16.7 | (3.57) | 16.2 | (4.28) | 16.5 | (3.84) | 0.154 |
| Pulse (beats/min) | 80.3 | (12.9) | 81.2 | (13.1) | 81.6 | (14.1) | 83.6 | (12.5) | 0.245 |
| SBP (mmHg) | 126 | (17.6) | 127 | (16.5) | 127 | (15.7) | 124 | (16.3) | 0.425 |
| DBP (mmHg) | 76.0 | (10.5) | 76.0 | (10.5) | 76.0 | (10.2) | 75.1 | (9.31) | 0.922 |
| Oxygen Saturation (%) | 97.3 | (1.67) | 97.2 | (1.59) | 97.2 | (1.56) | 97.0 | (2.06) | 0.453 |
| Temperature (°C) | 36.7 | (0.57) | 36.7 | (0.59) | 36.7 | (0.55) | 36.8 | (0.49) | 0.688 |
Numbers in bold denote statistical significance.