Table 3.
Symptom severity measured as the mean diary score for all symptoms during Days 2 to 4 after the baseline consultation in the prospective Cough Complication Cohort (3C) Plus study 2013
| Predictor | n | Symptom severity | Unadjusted | Adjusteda | |||
|---|---|---|---|---|---|---|---|
| Mean | (SD) | MD | (95% CI) | MD | (95% CI) | ||
| Organism group | |||||||
| None | 161 | 1.23 | (0.72) | - | Reference | - | Reference |
| Viral | 78 | 1.43 | (0.66) | 0.201 | (0.008 to 0.393) | 0.204 | (0.010 to 0.398) |
| Bacterial | 68 | 1.40 | (0.70) | 0.170 | (−0.032 to 0.371) | 0.192 | (−0.008 to 0.391) |
| Both | 38 | 1.63 | (0.79) | 0.392 | (0.140 to 0.644) | 0.348 | (0.098 to 0.598) |
| Haemophilus influenzae | |||||||
| No | 257 | 1.28 | (0.70) | - | Reference | - | Reference |
| Yes | 88 | 1.58 | (0.73) | 0.295 | (0.123 to 0.467) | 0.272 | (0.103 to 0.442) |
| Picornavirus b | |||||||
| No | 263 | 1.32 | (0.71) | - | Reference | - | Reference |
| Yes | 82 | 1.48 | (0.74) | 0.163 | (−0.015 to 0.341) | 0.116 | (−0.062 to 0.293) |
Numbers in bold denote statistical significance.
aAdjusted for age, antibiotic prescription and duration of illness. Analysis for specific organisms was also adjusted for viral co-infection for those with Haemophilus influenzae, and for bacterial co-infection for those with Picornavirus.
bPicornavirus group combines organisms identified as either in Enterovirus genus or Rhinovirus species.