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. 2019 Dec 17;37(3):332–339. doi: 10.1093/fampra/cmz093

Table 4.

Duration of symptoms rated by participants as moderate or severe after initial presentation (i.e. the last day on which a rating of moderate or severe was recorded in the diary for any symptom) in the prospective Cough Complication Cohort (3C) Plus study 2013

Predictor n Duration Unadjusted Adjusteda
Mean (SD) MD (95% CI) MD (95% CI)
Organism
 None 162 4.40 (2.53) - Reference - Reference
 Viral 78 4.65 (2.23) 0.25 (−0.39 to 0.89) 0.17 (−0.48 to 0.82)
 Bacterial 69 4.55 (2.30) 0.15 (−0.52 to 0.82) 0.18 (−0.49 to 0.85)
 Both 38 5.00 (2.03) 0.60 (−0.24 to 1.44) 0.51 (−0.33 to 1.35)
Haemophilus influenzae
 No 259 4.42 (2.42) - Reference - Reference
 Yes 88 4.94 (2.16) 0.52 (−0.05 to 1.09) 0.51 (−0.07 to 1.08)
Picornavirus b
 No 265 4.53 (2.44) - Reference - Reference
 Yes 82 4.63 (2.14) 0.11 (−0.48 to 0.69) −0.02 (−0.62 to 0.58)

aAdjusted for age, antibiotic prescription, and duration of illness. Analysis for specific organisms was also adjusted for viral co-infection for those with Haemophilus influenzae, and for bacterial co-infection for those with Picornavirus.

bPicornavirus group combines organisms identified as either in Enterovirus genus or Rhinovirus species.