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. 2020 Mar 31;66(4):616–618. doi: 10.1093/clinchem/hvaa026

Fig. 1.

Fig. 1.

Fragment size analysis of reads bearing mutations derived from tumor and CH in plasma cell-free DNA. Relative enrichment between tumor (positive values) and clonal hematopoiesis (CH) fragments (negative values), obtained by subtracting the normalized CH size profile from the normalized tumor profile. Shown in black is a LOESS fit. Colored areas denote the selected regions (orange for tumor, blue for CH).