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. 2017 Jul 20;75(7):ftx083. doi: 10.1093/femspd/ftx083

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© FEMS 2017. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.

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Figure 4. — NNT plot of all morbidity data from RCTs involving either antimicrobial prophylaxis (red circles) or metaphylaxis (black circles). Size of the circles reflects the sample size of the RCT (see the legend). Bolded circles are blinded RCTs. Green line represents the overall NNT median value = 7.27. The curve represents the expected NNT as a function of CER assuming a uniform RR (=0.52) across all values of CER. NNT, number needed to treat; ARR, absolute risk reduction; RCT, randomised clinical trial.