Table 2.
Predictors of Osteopenia and Osteoporosis in Patients With MACS
| Predictor | Multivariable Analysis | ||
|---|---|---|---|
| Odds Ratio | 95% CI | P Value | |
| Age (for every 10 yrs increase) | 1.20 | 0.57-2.53 | 0.83 |
| Female sex | 1.35 | 0.18-9.87 | 0.77 |
| BMI (for every 5 kg/m2 increase) | 0.94 | 0.49-1.80 | 0.85 |
| Osteocalcin (for every ng/mL increase) | 1.10 | 0.92-1.32 | 0.26 |
| PINP (for every 1µg/L increase) | 0.97 | 0.90-1.07 | 0.62 |
| CTX (for every ng/mL increase) | 2.44 | 0.0-3189 | 0.8 |
| Sclerostin (for every 100 pg/mL increase) | 0.63 | 0.40-0.98 | *0.04 |
| Cortisol after 1mg DST (for every 1 µg/dL increase) | 0.92 | 0.74-1.16 | 0.51 |
All P values < 0.05 were considered statistically significant.
BMI, Body mass index; PINP, N-terminal propeptide of type 1 collagen; CTX, C-terminal telopeptide of Type 1 collagen; DST, dexamethasone suppression test