Table 2. Fluconazole MIC values of cryptococcal isolates collected during 2 surveillance periods: 1 March 2007–28 February 2008 and January 2017 –March 2017.
MIC value (μg/ml) | Number (%) of isolates | |
---|---|---|
Feb 2007—Mar 2008 (n = 249) | Jan–Mar 2017 (n = 229) | |
0.125 | 0 (0) | 0 (0) |
0.25 | 1 (1) | 0 (0) |
0.5 | 14 (5) | 3 (1) |
1 | 53 (21) | 20 (9) |
2 | 97 (39) | 50 (22) |
4 | 70 (28) | 67 (29) |
8 | 14 (6) | 73 (32) |
16 | 0 (0) | 14 (6) |
32 | 0 (0) | 1 (0.5) |
64 | 0 (0) | 1 (0.5) |
Total | 249 | 229 |
Range | 0.25–8 | 0.5–64 |
MIC50 | 1 | 4 |
MIC90 | 2 | 8 |
Geometric mean | 2.08 | 4.11 |