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. 2020 Mar 31;14(3):e0008137. doi: 10.1371/journal.pntd.0008137

Table 2. Fluconazole MIC values of cryptococcal isolates collected during 2 surveillance periods: 1 March 2007–28 February 2008 and January 2017 –March 2017.

MIC value (μg/ml) Number (%) of isolates
Feb 2007—Mar 2008 (n = 249) Jan–Mar 2017 (n = 229)
0.125 0 (0) 0 (0)
0.25 1 (1) 0 (0)
0.5 14 (5) 3 (1)
1 53 (21) 20 (9)
2 97 (39) 50 (22)
4 70 (28) 67 (29)
8 14 (6) 73 (32)
16 0 (0) 14 (6)
32 0 (0) 1 (0.5)
64 0 (0) 1 (0.5)
Total 249 229
Range 0.25–8 0.5–64
MIC50 1 4
MIC90 2 8
Geometric mean 2.08 4.11