Skip to main content
. 2020 Mar 12;16(3):e1008391. doi: 10.1371/journal.ppat.1008391

Fig 1. ES-62 extends lifespan in male HCD-fed C57BL/6J mice.

Fig 1

Kaplan-Meier survival curves (a-c) for HCD-fed mice treated either with PBS or ES-62 were analysed as (a) combined sex cohorts (PBS, n = 48; ES-62, n = 48); (b) male mice (PBS, n = 24; ES-62, n = 24, *p<0.05) only and (c) female mice (PBS, n = 24; ES-62, n = 24) only. Median survival values for the relevant groups are shown as inserts. The data for the male and female cohorts are also presented as the frequency distribution of lifespan (d, male; e, female). Longitudinal analysis of body mass (BM; f) measurements was undertaken where data are presented as mean values ± SEM of the individual mice (Male, blue symbols; Female, red symbols) surviving at the indicated time-points.