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. 2020 Mar 30;40(8):e00471-19. doi: 10.1128/MCB.00471-19

FIG 1.

FIG 1

Upregulation of SP110 upon microbe infection or molecular treatment. (A) The expression of SP110 in an HBV-associated acute liver failure group was higher than in a normal-liver group. The values of HBV-associated acute liver failure groups were normalized to the mean of the normal-liver group (+SD). The GEO profile number is GDS4387 (GPL570 platform no. 209761_s_at). The data set title is “Hepatitis B virus (HBV)-associated acute liver failure (ALF) patients: liver explant” (58). **, P < 0.01. (B) Sendai virus infection effect on SP110 induction in a monocytic cell line. The values of Sendai virus-infected groups were normalized to the mean of the uninfected (UI) group (+SD). The GEO profile number is GDS6082 (GPL570 platform no. ILMN_2415144). The data set title is “Sendai virus infection effect on monocytic cell line: dose response” (59). (C) Pandemic and seasonal influenza virus H1N1 infection effect on SP110 induction in bronchial epithelial cells. The values of various H1N1 strain-infected groups were normalized to the mean of the UI group (+SD). The GEO profile number is GDS4855 (GPL570 platform no. 208012_x_at). The data set title is “Pandemic and seasonal H1N1 influenza virus infections of bronchial epithelial cells in vitro” (60). (D) Effect of H37Rv infection on SP110 induction in THP-1 cells. The values of the H37Rv-treated group were normalized to the mean of the UI group (+SD). The GEO profile number is GDS4781 (GPL570 platform no. 8059650). The data set headline is “Mycobacterium tuberculosis H37Rv-infected macrophage response to vitamin D” (61). (E) Effect of Mycobacterium bovis BCG infection on SP110 induction in THP-1 cells. The values of the BCG-treated group were normalized to the mean of the UI group (+SD). The GEO profile number is GDS2180 (GPL570 platform no. AGhsA070521). The data set title is “M-CSF and GM-CSF differentiated macrophage response to bacillus Calmette-Guerin (subset A)” (62). (F) The expression of SP110 in the etoposide-treated group was higher than that in the negative-control (NC) group. The values of the etoposide-treated group were normalized to the mean of the NC group (+SD). The GEO profile number is GDS5809 (GPL570 platform no. 8059650). The data set heading is “Anti-leukemia drug etoposide effect on ecotropic viral integration site 1-overexpressing myeloid cells” (63). (G) Cytarabine treatment leading to SP110 induction. The values of the DMSO-, doxorubicin-, puromycin-, and cytarabine-treated group were normalized to the mean of the DMSO (24-h) group (+SD). The GEO profile number is GDS2733 (GPL570 platform no. 208012_x_at). The data set headline is “Cytosine arabinoside effect on Ewing’s sarcoma cell line: time course and dose response” (64).