FIG 2.

Relative fibroblast and epithelial cell tropism of parental and heterologous gO recombinant HCMV. Cell-free stocks of HCMV TR (A), ME (B), or MT (C) or the corresponding heterologous gO recombinants were serially diluted, and side-by-side cultures of nHDF (Fib) and ARPE19 epithelial cells (Epi) were inoculated with equal volumes of the dilutions. The number of infected cells was determined by flow cytometry for GFP at 2 days postinfection. Ratios greater than or equal to 1 of the number of each cell type infected (Fib/Epi or Epi/Fib) are plotted for each of three independent sets of virus stocks (black, open, and hatched bars).