TABLE 2.
Comparison of amino acid sequences of nonstructural regions of RRV 2548 and RRV-T48
| nsP | Length (aa)a | No. of substitutions | Substitutions (RRV-T48 to 2548) |
|---|---|---|---|
| nsP1 | 534 | 4 | V186A, I278V, E402A, R522Q |
| nsP2 | 798 | 8 | R11K, A31T, E116D, V123I, E167D, N219T, S580L, Q619R |
| nsP3 | 538 (RRV-T48) | 12b | T28A, Q59R, N279S, K323Q, T331M, RADTVSLDSSVL 332–343 (insertion)b |
| 550 (RRV 2548) | V419A, E436G, K439T, C505R, K506E, V520I, S530P | ||
| nsP4 | 611 | 6 | V41A, T98I, K106R, R116L, L235F, V450I |
a
aa, amino acids.
b
There is a 12-amino-acid insertion in nsP3 of RRV 2548.