TABLE 1.
Sequence variation at the HA cleavage site in spleen and lung samples of H7N3-infected turkeys
| Spleen CS |
Lung CS |
||
|---|---|---|---|
| Sequencea | No. (%) of reads (n = 35,220) | Sequencea | No. (%) of reads (n = 45,384) |
| PEIPKGRGLF | 34,402 (97.68) | PEIPKGRGLF | 42,271 (93.14) |
| PEIPKGRGLL | 91 (0.26) | PEIPKGSRVRRGLFb | 1,990 (4.38) |
| PEIPKGGGLF | 84 (0.24) | PEIPRGRGLF | 116 (0.26) |
| PEIPRGRGLF | 66 (0.19) | PEIPKGGGLF | 112 (0.25) |
| PEISKGRGLF | 55 (0.16) | PEIPKGRGLL | 108 (0.24) |
| PEILKGRGLF | 41 (0.12) | PETPKGRGLF | 59 (0.13) |
| PEIPKGRGPF | 37 (0.11) | PEILKGRGLF | 56 (0.12) |
| PETPKGRGLF | 36 (0.10) | PEIPKGRGPF | 51 (0.11) |
| PEIPEGRGLF | 26 (0.07) | PEVPKGRGLF | 36 (0.08) |
| PEVPKGRGLF | 26 (0.07) | SEIPKGRGLF | 35 (0.08) |
| PEIPKGRGLS | 25 (0.07) | PEIPKGRGLS | 34 (0.07) |
| SEIPKGRGLF | 23 (0.07) | PEIPEGRGLF | 34 (0.07) |
| PEIPKRRGLF | 21 (0.06) | PEIPKGRSLF | 30 (0.07) |
| TEIPKGRGLF | 21 (0.06) | PEIPKGKGLF | 28 (0.06) |
| LEIPKGRGLF | 15 (0.04) | PEIPKGRDLF | 27 (0.06) |
| PGIPKGRGLF | 14 (0.04) | LEIPKGRGLF | 26 (0.06) |
| PKIPKGRGLF | 13 (0.04) | PEISKGRGLF | 25 (0.06) |
| PEIPKGRDLF | 13 (0.04) | PEIPKRRGLF | 24 (0.05) |
| PEIPKGSRVRRGLFb | 12 (0.03) | TEIPKGRGLF | 22 (0.05) |
| PEIPKGRSLF | 11 (0.03) | PKIPKGRGLF | 20 (0.04) |
| Other | 188 (0.53) | Other | 280 (0.62) |
| Total | 35,220 (100.00) | Total | 45,384 (100.00) |
a
All sequences listed, except as noted, were 10 aa in length.
b
Highly pathogenic HA cleavage site (14 aa).