Table 2.
Characteristics and Clinical Parameters of Obese Adolescents According to Leptin Levels
| Parameters | ObeseNL (n= 25) | ObeseHL (n=26) | P-value |
|---|---|---|---|
| Age (years) | 17.60 ± 0.20 | 18.00 ± 0.20 | 0.30 |
| Female (%) | 48 | 73 | 0.06 |
| BMI (kg/m2) | 27.74 ± 0.53 | 30.25 ± 0.79 | 0.01* |
| WC (cm) | 91.04 ± 1.40 | 94.21 ± 1.95 | 0.19 |
| Body fat (%) | 26.41 ± 1.10 | 31.32 ± 1.09 | 0.002* |
| SBP (mmHg) | 125.16 ± 2.12 | 121.84 ± 1.85 | 0.24 |
| DBP (mmHg) | 75.84 ± 1.53 | 73.69 ± 1.74 | 0.35 |
| Heart rate (beats/min) | 79.00 [76.00–88.00] | 78.50 [72.25–86.25] | 0.47 |
| Uric acid (mg/dL) | 4.42 ± 0.22 | 3.82 ± 0.27 | 0.10 |
| Leptin | 17.16 ± 0.8 | 47.16 ± 2.25 | <0.001** |
| Triglyceride (mg/dL) | 159.43 ± 11.23 | 159.72 ± 10.77 | 0.98 |
| Cholesterol (mg/dL) | 164.60 [151.30–183.50] | 165.20 [151.60–197.20] | 0.84 |
| HDL (mg/dL) | 41.77 ± 1.37 | 41.13 ± 1.67 | 0.79 |
| LDL (mg/dL) | 98.23 ± 6.24 | 97.03 ± 6.06 | 0.88 |
| Hb (g/dL) | 13.75 ± 0.38 | 12.55 ± 0.33 | 0.02* |
| WBC (x103/μL) | 5.70 ± 0.36 | 6.08 ± 0.23 | 0.37 |
Notes: Values are mean ± SEM or median [25th–75th percentile] or n (%). *p < 0.05 and **p < 0.01 of statistically significant difference between obese adolescents with normoleptinemia (ObeseNL) and hyperleptinemia (ObeseHL).
Abbreviations: BMI, body mass index; DBP, diastolic blood pressure; Hb, hemoglobin; HDL, high-density lipoprotein; LDL, low-density lipoprotein; SBP, systolic blood pressure; WBC, white blood cells; WC, waist circumference.