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. 2020 Mar 16;130(4):2069–2080. doi: 10.1172/JCI130197

Figure 5. Association of plasminogen level at admission with HBV-ACLF prognosis and organ failure.

Figure 5

(A) Plasminogen distribution for patients with HBV-ACLF in both the derivation and validation cohorts. Prediction of 30-day mortality according to plasminogen levels in patients with HBV-ACLF in the (B) derivation and (D) validation cohorts. Survival rates after 30 days of patients in the high- and low-plasminogen groups in the (C) derivation and (E) validation cohorts. Plasminogen levels at admission decreased with (F) increasing numbers of failed organs. Plasminogen distribution of HBV-ACLF patients with and without (G) liver failure (LF) , (H) coagulation failure (CoF) , (I) cerebral failure (CeF), (J) respiratory failure (RF), and (K) circulation failure (CF) in the derivation and validation cohorts. Plasminogen levels were compared using the Mann-Whitney U test, rank correlation was analyzed by the Spearman method, and Kaplan-Meier plots were compared by log-rank test. *P < 0.05 and ***P < 0.001.