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. 2020 Mar 16;130(4):2041–2053. doi: 10.1172/JCI129635

Figure 1. Lung injury and bacterial lung colony measurements in CF mice after intratracheal LPS or PAO1.

Figure 1

(A and G) BAL WBCs, (B and H) BAL neutrophils, (C and I) BAL total protein, (D and J) BAL thromboxane B2, and BAL NETs as measured by (E and K) NE-DNA and (F and L) citH3-DNA in WT, CFTR+/–, and CFTR–/– mice at 48 hours after intratracheal LPS or PAO1. (M) Bacterial lung colony counts in WT, CFTR+/–, and CFTR–/– mice after intratracheal PAO1. Data are mean ± SEM of 5 to 8 animals per group. Data were analyzed by 1-way ANOVA. *P ≤ 0.05; **P ≤ 0.01; ***P ≤ 0.001.