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. 2020 Mar 3;130(4):1850–1862. doi: 10.1172/JCI134057

Figure 2. Mixed-meal tolerance test (MMTT).

Figure 2

(A and B) Serum C-peptide response to ingestion of a standardized liquid meal was different by group based on peak C-peptide level (negative, <0.007 pmol/mL [<0.02 ng/mL]; low, 0.017–0.200 pmol/mL [0.05–0.60 ng/mL]; intermediate, >0.200–0.400 pmol/mL [>0.60–1.20 ng/mL]; high, >0.400 pmol/mL [>1.20 ng/mL]), and by continuous relationship to peak C-peptide. (C and D) Plasma glucagon response was not different while plasma glucose-dependent insulinotropic polypeptide (GIP) response was different in response to meal ingestion by peak C-peptide level group. Data are means with error bars denoting 95% confidence intervals (CIs).