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. Author manuscript; available in PMC: 2021 Apr 1.
Published in final edited form as: Mol Imaging Biol. 2020 Apr;22(2):384–396. doi: 10.1007/s11307-019-01382-x

Table 4.

ROC analysis of Type-4 normalized APT-w contrast corresponding to ROI-2 to differentiate low grade glioma (LGG) and infective mass lesions.

HP p value (post hoc) Sensitivity (%) Specificity (%) AUC (lb, ub) (%) cut-off (%) Accuracy (%)
mean 0.04 62.5 71.43 73.21(51, 95) 4.77 68.18
SD 0.04 87.5 50 71.4(46, 96) 0.58 81.81
median 0.05 62.5 71.43 74.1(53, 95) 4.68 68.18
mtop10 0.04 62.5 71.43 73.2(51, 95) 4.39 68.18
mtop25 0.03 87.5 57.14 75(54, 96) 4.46 68.18
mtop50 0.02 75 71.43 76.8(56, 97) 5.21 72.72
mtop75 0.01 75 71.43 75.9(55, 96) 5.60 72.72
mtop90 0.01 75 71.43 75(53, 96) 5.78 72.72
sdtop25 0.03 62.5 78.57 71.4(45, 97) 0.64 72.72

AUC – area under curve;

lb and ub are lower and upper bound with 95% confidence interval;

HP -histogram parameters