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. 2019 Dec 2;59(4):447–462. doi: 10.1007/s40262-019-00844-3

Table 6.

Medications with no clinically meaningful interaction with one or more acid-reducing agents (n = 109)

Acitretin Donepezil Lisdexamfetamine Sertindole
Alectinib Dronedarone Lopinavir and ritonavir (Kaletra®) Sildenafil
Ambrisentan Duloxetine Losartan Sodium oxybate
Amlodipine Efavirenz Meloxicam Sorafenib
Aripiprazole Elbasvir and grazoprevir (Zepatier®) Metronidazole Sulfasalazine
Asenapine Eliglustat Moexipril Sulindac
Aspirin Eprosartan Naproxen DR Tapentadol
Aspirin/extended-release dipyridamole (Aggrenox®) Etravirine Nebivolol Telithromycin
Axitinib Ezetimibe Nevirapine Temozolomide
Azacitidine Famciclovir Nifedipine Topotecan
Betrixaban Febuxostat Nintedanib Tramadol
Boceprevir Fenofibric acid Obeticholic acid Trandolapril
Bortezomib Fenoprofen Osimertinib Ulipristal acetate
Brexpiprazole Fluconazole Oxcarbazepine Valacyclovir
Cabozantinib Fluvastatin Palbociclib Valproic acid
Carvedilol Fosamprenavir Paricalcitol Valsartan
Cephalexin Gabapentin Pioglitazone Vandetanib
Ceritinib Gabapentin enacarbil Piroxicam Venlafaxine
Cobimetinib Garenoxacin Ponatinib Vilazodone
Crizotinib Glecaprevir/pibrentasvir (Mavyret™) Posaconazole delayed release capsules Vismodegib
Dabigatran etexilate mesylate Glimepiride Prasugrel Vorapaxar
Danoprevir Imatinib Propranolol Voriconazole
Dapsone Indinavir Raloxifene Zolpidem
Darunavir Isavuconazonium sulfate Ramelteon
Diazepam Isoniazid Repaglinide
Diclofenac Itraconazole oral suspension Risperidone
Digoxin Lamotrigine Rivaroxaban
Divalproex Letrozole Saxagliptin

Medications were identified via searches and screens of the PDR3D: Reed Tech Navigator™, University of Washington Drug–Drug Interaction Database (DIDB), and DailyMed databases as detailed in Sect. 4.1

DR delayed release