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. 2020 Jan 9;267(4):1147–1157. doi: 10.1007/s00415-019-09672-8

Table 1.

Demographic, neuropsychological and behavioural data

Units PSP CBS p value (t test, χ2)
Mean/% SD N Mean/% SD N
Demography
 Age Years 70.6 7.9 25 70.3 9.1 30 ns
 Sex %Male 60 25 37 30 ns
 Handedness % R 96 25 97 30 ns
Neuropsychology
ACE-R total /100 79.1 10.4 25 70.0 13.7 29 0.008
 Attention and orientation /18 16.4 1.8 25 15.0 2.7 29 0.028
 Memory /26 21.1 4.3 25 17.2 4.7 29 0.002
 Verbal fluency /14 5.6 3.2 25 7.6 2.9 29 0.027
 Language /26 23.0 2.3 25 21.9 2.5 29 ns
 Visuospatial /16 13.4 4.3 25 8.4 4.5 29  < 0.001
MMSE /30 26.4 2.8 25 23.1 4.5 30 0.002
FAB /18 10.9 4.3 25 10.4 4.7 28 ns
Motor examination
UPDRS-III /108 32.2 13.3 25 24.7 9.9 19 0.038
Praxis total limb /20 19.1 2.1 24 9.3 5.2 30  < 0.001
 Transitive mime /6 5.7 1.0 24 3.0 2.0 30  < 0.001
 Intransitive mime /6 5.9 0.4 24 3.7 1.9 30  < 0.001
 Unilateral imitation /6 5.7 0.9 24 2.2 1.8 30  < 0.001
 Bilateral imitation /2 1.8 0.6 24 0.4 0.7 30  < 0.001
 Orofacial /2 2.00 0.0 22 1.79 0.6 28 ns
Alien limb questionnaire /13 0.08 0.4 25 4.23 3.1 30  < 0.001

PSP-RS Progressive supranuclear palsy Richardson syndrome, CBS corticobasal syndrome, ACE-R Addenbrooke’s Cognitive Examination-Revised, MMSE Mini-Mental State Examination, FAB Frontal Assessment Battery, UPDRS-III Unified Parkinson’s Disease Rating Scale (part III motor subscale)

p values < 0.05 were considered statistically significant