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Vaccine efficacy parameters
| Parameter | Value |
|---|---|
| Protection against invasive disease | 85% (Vesikari et al. 2016) |
| Protection against carriage | 26.6% (Read et al. 2014) |
| Duration of protection against disease | 5 years (Vesikari et al. 2017) |
| Duration of protection against carriage | 5 years (Vesikari et al. 2017) |
| Annual decrease in protection against disease | 10% (assumption) |
| Annual decrease in protection against carriage | 20% (assumption) |
