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. 2020 Mar 25;11:478. doi: 10.3389/fimmu.2020.00478

Figure 3.

Figure 3

Production of cytokines and chemokines in the supernatants of biopsy cultures of lesion (psoriatic patients) and skin (healthy subjects). (A) Biopsies (4 mm) were obtained from lesions of psoriatic patients (N = 26) and skin from healthy subjects (HS) (N = 14) and cultured for 48 h. Cytokine and chemokine (TNF, IL-1β, CXCL9, and CCL2) concentrations were determined by ELISA (results presented in pg/ml). The Mann-Whitney test was used to compare medians between groups. (B) Correlation between CCL2 levels in cultured supernatants from patients with psoriasis and disease severity (PASI). Data were analyzed using Spearman's correlation testing.