TABLE 1.
Acidic end-products | ||||
Substrate | Acetate | Formate | Lactate | |
pH 7.0 | G (−) F (−) | 27.2 ± 5.5† (78.4)‡ | 7.52 ± 1.8 (21.6) | ND |
G (+) F (−) | 90.4 ± 8.9 (74.4) | 31.1 ± 3.5 (25.6) | ND | |
G (+) F (2.5) | 80.3 ± 8.1 (74.4)** | 27.6 ± 3.7 (25.6) | ND | |
G (+) F (5) | 67.1 ± 8.3 (76.0)** | 21.1 ± 2.9 (24.0)** | ND | |
G (+) F (10) | 55.8 ± 11.7 (81.6)** | 12.6 ± 8.2 (18.4)** | ND | |
G (+) F (20) | 54.0 ± 7.4 (85.1)** | 9.46 ± 2.9 (14.9)** | ND | |
pH 5.5 | G (−) F (−) | 27.6 ± 5.8 (78.5) | 7.56 ± 2.1 (21.5) | ND |
G (+) F (−) | 104.8 ± 11.1 (71.4) | 22.9 ± 3.1 (15.6) | 19.0 ± 1.8 (12.9) | |
G (+) F (0.5) | 86.9 ± 9.2 (74.7)** | 25.5 ± 2.6 (21.9)* | 3.97 ± 0.9 (3.4)* | |
G (+) F (1) | 76.0 ± 7.6 (77.7)** | 21.8 ± 2.5 (22.3) | ND | |
G (+) F (2) | 63.0 ± 7.9 (82.3)** | 13.6 ± 2.9 (17.7)** | ND | |
G (+) F (4) | 67.4 ± 9.6 (91.2)** | 6.54 ± 1.1 (8.8)** | ND |
†Data are presented as the mean and standard deviation of three independent experiments (μM/OD). ‡Relative amount of each acidic end-product compared with the total amount of acidic end-products (%). G, 10 mM glucose; F, fluoride (mM). *P < 0.05; **P < 0.01; compared with the amount of acidic end-products produced in the presence of glucose.