TABLE 1.
Usage | Dataset | Regimen | ER-negative sample size | pCR | RD | With DRFS information |
Training | GSE20194 Popovici et al. (2010) | T-FA(E)Ca | 114 | 46 | 68 | no |
GSE20271 Tabchy et al. (2010) | T-FA(E)C | 79 | 19 | 60 | no | |
MDA133 Hess et al. (2006) | T-FAC | 51 | 27 | 24 | no | |
GSE41998 Horak et al. (2013) | T-ACb | 48 | 29 | 19d | no | |
Validation | GSE25055 Hatzis et al. (2011) | T-AC;TAc | 129 | 45 | 84 | yes |
GSE25065 Hatzis et al. (2011) | TA | 68 | 23 | 45 | yes |
aT-FA(E)C paclitaxel (T) followed by fluorouracil (F), doxorubicin (A) [or epirubicin (E)] and cyclophosphamide (C). bT-AC doxorubicin (A) and cyclophosphamide (C) followed by paclitaxel (T). cTA taxane (T) and anthracycline (A) based regimens. dPD and SD samples representing tumor residuals screened from RD samples.