Figure 5.

Peptide-pulsed, CFSE-labeled, HLA-matched targets were incubated with CD8+ T cell line effector cells, and the percent specific killing was measured by flow cytometry in response to JEV and DENV/ZIKV peptides. Percent killing (A) and the percent of CD107+ CD8+ T cells (B) are shown. Diamonds indicate T cell lines expanded with JEV peptide, and squares indicate lines expanded with DENV/ZIKV peptide. Assays were performed in duplicate for each T cell line/peptide pair. Error bars represent standard error of the mean. This figure was adapted from Turtle et al. (20).