TABLE 4.

Pig PK study plan.

Parameters			EDTA plasma						Organs
Intervention	Substance	Dosing	15 min	30 min	1 h	6 h	12 h	24 h	Heart	Liver	Kidney	Brain	Lung	Spleen	Ovary	Skin	Fat	Muscle
i.c.	antimiR132	0.5 mg/kg	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X
i.c.	antimiR132	1.17 mg/kg	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X
i.c.	antimiR132	5 mg/kg	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X
i.c.	NaCl	–						X	X	X	X	X	X	X	X	X	X	X
Control	Control	Control						X	X	X	X	X	X	X	X	X	X	X