TABLE 1.

Three class divided according to physicochemical property.

Physicochemical property	the 1st class	the 2nd class	the 3rd class
hydrophobicity	RKEDQN	GASTPHY	CVLIMFW
Normalized van der Waals volume	GASCTPD	NVEQIL	MHKFRYW
polarity	LIFWCMVY	PATGS	HQRKNED
polarizability	GASDT	CPNVEQIL	KMHFRYW
charge	KR	ANCQGHILMFPSTWYV	DE
surface tension	GQDNAHR	KTSEC	ILMFPWYV
secondary structure	EALMQKRH	VIYCWFT	GNPSD
solvent accessibility	ALFCGIVW	RKQEND	MPSTHY