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. 2020 Feb 20;4(4):527–539. doi: 10.1002/hep4.1487

Table 1.

Hepatic Fatty Acid Composition in Mice Fed an Alcohol Diet (μg/mg)

Fatty Acids Control Diet Control Diet EtOH Diet EtOH Diet
AAV‐Null AAV‐hCES1 AAV‐Null AAV‐hCES1
C14:0 0.128 ± 0.02 0.106 ± 0.017 0.308 ± 0.09 0.121 ± 0.02§
C16:0 21.93 ± 3.36 37.49 ± 10.17 48.38 ± 4.98 34.26 ± 2.73§
C16:1 0.338 ± 0.05 0.366 ± 0.06 0.768 ± 0.205 0.178 ± 0.037||
C18:0 7.68 ± 0.31 6.2 ± 0.35*, 12.85 ± 1.13*, 8.41 ± 0.38||
C18:1 25.27 ± 3.63 27.36 ± 3.22 61.71 ± 10.41*, 42.77 ± 0.65
C18:2 11.64 ± 1.85 10.7 ± 1.26 43.36 ± 5.85 27.31 ± 1.78§
C20:4 0.53 ± 0.15 0.146 ± 0.04*, 0.225 ± 0.05*, 0.023 ± 0.007||
C22:6 7.99 ± 2.26 2.57 ± 0.51*, 3.34 ± 0.776*, 0.912 ± 0.05§

C57BL/6 mice were injected with AAV8‐ALB‐Null or AAV8‐ALB‐hCES1 and fed a control diet or EtOH diet. Hepatic fatty acid composition was analyzed by GC‐MS.

*

P < 0.05 versus control diet–fed AAV‐Null group.

P < 0.05.

P < 0.01 versus control diet–fed AAV‐Null group.

§

P < 0.05.

||

P < 0.01 versus EtOH diet–fed AAV‐Null group.