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. 2020 Mar 19;7:468–474. doi: 10.1016/j.toxrep.2020.03.003

Table 5.

Reference dose for trace metals.

Heavy metal Reference dose (RfD)
REFERENCE
Inhalation (mg/m3) Oral (mg/kg/ day)
Chromium 1.00E-4 3.00E-3 EPA
Manganese 5.00E-5 1.40E-1 EPA
Copper 1.43E-1 ± 2.25E-2 4.00E-2 RAIS
Nickel 9.00E-5 2.00E-2 EPA
Cobalt ND by EPA 3.00E-2 RTP
Arsenic 4.3E-6 3.00E-4 EPA
Cadmium 1.00E-5 1.00E-3 EPA/ATSDR
Lead ND by EPA 3.5E-3 ND by EPA

*ND = Not Determined. RTP (see ref [31]).